About us

What we do

The CAN.HEAL consortium recognises that prevention, diagnosis and treatment should be approached in a concerted way for optimal benefit of patients and citizens. We focus on applying ‘next generation sequencing’ technology and identifying implementation paths to extend the application of genetic profiling to structure omics use in patient care, share data among EU Cancer Centres which would improve equity in treatment, and allow better counselling regarding cancer risk using molecular tumour profiling biomarkers. We wish to set the framework for integrating the Genome of Europe biobanking initiative into public health genomics for cancer.

WP1 Project management and coordination

WP2 Communication, dissemination and outreach

WP3 Evaluation

Genomics for public health

WP4 Biobanking - Genome of Europe

WP5 Polygenic Risk Scores (PRS) and Decision Support Tools

WP6 Building Clinical utility

cancer diagnostics and treatment for all

WP7 Prevention and early detection

WP8 Diagnosis and treatment decision via MTB (molecular tumor boards)

WP9 Treatment and follow-up

WP10 Oncology Decision Support Tools

WP11 NGS including Liquid Biopsy

WP12 Law, ethics and citizen engagement

WP13 Training and education

WP14 Healthcare system implementation

Summary

Build on distinct use cases towards developing an integrated approach to improve access of individuals and cancer patients and survivors to prevention , diagnosis and treatment of cancer through personalised medicine.

Genomics for Public Health:

Framework for aligning and integrating the genome of Europe biobanking
Polygenic risk score analysis/recommendations for decision support tools and strategies for the implementation of telegenetics and remote genetic counselling
Building clinical utility for cancers in pregnancy, family based genetic testing in pediatric leukemia, cancer risk stratification

Cancer diagnostics and treatment for all:

Strategies for wet lab tools, comprehensive genomic profiling , data interpretation, data integration, decision support (MTB and tools) for early detection, diagnosis and treatment
Implementing NGS based and liquid biopsy assays in clinical practice

Define key legal and ethical requirements for cancer genomics.

Develop training tools.

Develop recommendations for the implementation of personalized approaches in the healthcare system.

Mission

Our goal is to support the development of effective cancer prevention strategies and policies and implement personalised medicine approaches for all cancer patients in Europe. We are working towards developing an integrated approach to improve access of individuals to prevention, diagnosis, and treatment of cancer through personalised medicine, by upscaling available innovation in the field of innovative cancer diagnosis and treatment.

Setting up a network of cancer centres across Europe by creating a European Cancer Patient Digital Centre will certainly help transform cancer culture and communication among stakeholders and improve the quality of life of cancer patients and survivors, their family members and carers, and everyone with an increased risk of cancer.

Our mission is to raise awareness of cancer predisposition to prevent and predict cancer, diagnose early on and treat the correct targets, as well as to transfer knowledge and expertise to patient care.