The CAN.HEAL project has contributed to the advancement of precision oncology, public health genomics, and data-driven healthcare innovation across Europe. Through its research and stakeholder collaborations, the project has established a framework to integrate genomic medicine into national cancer strategies and healthcare systems.
Key outcomes of CAN.HEAL include:
- Molecular Tumor Boards (MTBs): Standardized guidelines for MTBs across European institutions to improve decision-making in precision oncology.
- National Genomic Initiatives: Mapping of genomic programs across EU member states, identifying best practices and gaps in implementation.
- Polygenic Risk Scores (PRS) and Cancer Prediction: Investigation of PRS portability across diverse populations and the identification of protective genomic loci.
- Ethical and Legal Compliance in Data Governance: Development of guidelines to ensure genomic data is managed in alignment with GDPR and the European Health Data Space (EHDS).
- Oncogenomic Data Reuse: Analysis of patient and citizen perspectives on genomic data sharing, addressing concerns around privacy, consent, and trust.
- EU-oncDST Decision Support Tool: Conceptualization of an AI-driven system to assist clinicians in interpreting genomic data for cancer treatment.
The CAN.HEAL Cluster Roadbook further outlines pathways for integrating these advancements into broader EU initiatives, aligning with Europe’s Beating Cancer Plan and the Digital Europe Programme.
These findings will support continued innovation and policy development in genomic medicine, ensuring equitable access to precision diagnostics and treatment for all cancer patients in Europe. Detailed reports can be found below.